SCIENTIFIC PROGRAMME

05/11/2026 - Evidence & Immunotherapy

08:00 - 09:00 | Registration & Coffee
09:00 - 09:10 | Welcome & Opening Remarks
Andreas Dietz, René Leemans, Wojciech Golusinski, Peter Klussmann

09:10 - 09:30 | Keynote Lecture
Global variations in the management of head and neck cancer reflecting complex interactions between training models, resource settings, and cultural paradigms
Chair: Giovanni Succo, Christian Simon
Speaker: Nicolas Fakhry

09:30 - 10:30 | Session A - early cancer
Chair: René Leemans, Thomas Hoffmann

• Talk 1: Update transoral approaches in T1,2 p16+ OPHNSCC
  Christian Simon
• Talk 2: Transoral ultrasound guided surgery (TOUSS)
  Mario Fernandez
• Talk 3: Transoral approaches TML in T1,2 p16+ OPHNSCC
  Susanne Wiegand
• Talk 4: Radiation: better not to operate in T1,2 p16+ OPHNSCC?
  Hans Langendijk

10:30 - 11:30 | Session B - locally advanced
Chair: Wojciech Golusinski; Andreas Dietz

• Talk 1: Is there a place for surgery in p16+ LA OPHNSCC
  Giovanni Succo
• Talk 2: Why not to operate on p16+ LA OPHNSCC
  Jeppe Friborg
• Talk 3: Perioperative IO in p16+ LA OPHNSCC
  Kevin Harrington
• Talk 4: Role of adjuvant IO in surgically treated p16+ versus p16- LA OPHNSCC
  Jean Bourhis

11:30 - 12:45 | Session C - Liquid Biopsy, Screening, follow up surveillance, treatment guidance
Chair: Chia-Jung Busch; Jochen Heß

Screening:
• Talk 1: Predictive value of HPV screening testing
  Tim Waterboer
• Talk 2: surrogate biomarkers for early lesions
  Paolo Bossi
Surveillance:
• Talk 3: Lessons learned from the Hamburg City Health Study
  Friederike Meyer
• Talk 4: Circulating HPV DNA
  Ruud Brakenhoff
Treatment guidance:
• Talk 5: Clinik ready for ctDNA-guided CRT for HPV+ OPC
  Inge Tinhofer-Keilholz

13:10 - 14:00 | Lunch Break, Posters & Industry Exhibition
Industrial Lunch Symposium - MSD Sharp & Dohme GmbH

14:00 - 14:20 | Keynote Lecture
Caveats and misleads of active HPV-vaccination strategies
Chair: Simon Laban; Amanda Psyrri
Speaker: Christian Ottensmeier

14:20 - 15:10 | Session D - therapeutic vaccination
Chair: Christian Ottensmeier, Markus Pirlich

• Talk 1: current trials landscape of therapeutic HPV-vaccination
  Amanda Psyrri
  
• Talk 2: neoadjuvant vaccination in surgical treatment of p16+ HNSCC
  Peter Klussmann
  
• Talk 3: Improving the translatability of preclinical therapeutic HPV vaccine testing
  Angelika Riemer

15:10 - 15:40 | Coffee Break, Posters & Industry Exhibition

15:40 - 16:00 | Keynote Lecture
Trends among Investigators for Suspected p16 pos. HNSCC of Unknown Primary
Chair: Chia-Jung Busch, Sefik Hosal
Speaker: Paul Nankivell

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06/11/2026 - Surgery, Function & De-Escalation

08:30 - 09:00 | Welcome & Coffee

09:00 - 09:20 | Keynote Lecture
Landscape of HPV related oropharyngeal cancer in Europe and Its Medical Consequences
Chair: Inbar Finkel, Linda Marklund
Speaker: Wojciech Golusinski

09:20 - 10:00 | Session F - Functional Outcomes and assessment tools
Chair: Viktor Kunz, Alexander Rühle

• Current view on PROMS and Frailty assessment
  Camilla Dorson
• Role of prehabilitation
  Markus Blaurock

10:00 - 11:30 | Session G - news in molecular insights into HPV+ OPC oncogenesis
Chair: Silke Tribius, Hisham Mehanna

• Talk 1: genomic and viral heterogeneity in HPV-related oropharyngeal carcinoma
  Sid Puram
• Talk 2: Genetic susceptibility to HPV-associated carcinomas
  Sharma Virani
• Talk 3: Using AI to stratify HPV-related oropharyngeal carcinoma
  Yuri Tolkach
• Talk 4: p16 and HPV discordance, meaning of false-positive p16
  Hisham Mehanna
• Talk 5: HPV-related methylation signature predicts survival in HNSCC
  Jochen Hess
• Talk 6: Time for early detection of HPV-driven HNSCC
  Chia-Jung Busch

11:30 - 12:15 | Coffee Break, Posters & Industry Exhibition
Industrial Symposium

12:15 - 13:00 | Session H - proffered papers
Chair: Sefik Hosal, Gunnar Wichmann

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Practical implications from the PATHOS-trial
Chair: Silke Tribius, Barbara Wollenberg
Speaker: Terry Jones

13:20 - 13:40 | Keynote Lecture
Immune Landscape of HPV positive disease
Chair: René Leemans, Susanne Wiegand
Speaker: Barbara Wollenberg

13:40 | Poster ceremony, Final Remarks & Farewell
Andreas Dietz, René Leemans, Wojciech Golusinski, Peter Klussmann

14:00 End of conference